HomeLifestyleMonkeypox can cause neurological damage, including brain swelling, study says

Monkeypox can cause neurological damage, including brain swelling, study says

monkeypox Skin effects – disfiguring rashes – and flu-like symptoms have been well described, but few have investigated the neurological and mental problems that the virus may cause.

There are historical reports of neurological complications in people infected with smallpox viruses and those who have been vaccinated against smallpox, including the related vaccinia virus. So my colleagues and I wanted to know if monkeypox causes similar problems.

We a. looked at all the evidence before the current monkeypox epidemic of neurological or mental problems in people with monkeypox infection, The results have been published in the Journal of Clinical Medicine.

A small but noticeable proportion (2% to 3%) of people with monkeypox became very unwell and developed serious neurological problems, including seizure and encephalitis (inflammation of the brain that can cause long-term disability). We also found that the same number of people were confused. However, it is important to note that these figures are based on a few studies with few participants.

In addition to serious and rare brain problems, we found evidence of a broader group of people with monkeypox who had more common neurological symptoms, including headache, muscle pain, and fatigue.

Monkeypox is caused by monkeypox virus, a member of the orthopoxvirus genus in the family Poxviridae. (Representational/WikiCommons)
It was not clear from looking at the studies how severe these symptoms were and how long they lasted. It was also unclear how many people with monkeypox had mental problems – such as anxiety and depression – as some studies looked at. Of those who did, low mood was most often reported.

We don’t know what factors are driving these neuropsychiatric problems in people with monkeypox. We would like to know whether the strain of monkeypox virus and the severity of infection affect these problems. However, we were not able to look into this precisely because it was not consistently reported in studies.

Although we found that people with monkeypox infection may have neuropsychiatric symptomsThe studies in our paper cannot say with any certainty that the virus is the cause of these problems. Future research investigating this will need to follow people with no neuropsychiatric conditions before they become infected with monkeypox.

If it is the virus that is causing these problems, the biological processes underlying it are unclear and may involve the virus entering the nervous system directly, a response by the immune system or something else entirely. It is also possible that the stigma and discoloring effect of skin rashes that people experience from monkeypox infection may contribute to psychological distress such as low mood.

Our research focused on evidence from before the current monkeypox epidemic. Most of the data was from West Africa and in people hospitalized from the infection, while the current pandemic has mainly affected North America and Western Europe. It is not clear to what extent symptoms from past outbreaks will reflect what we are seeing now.
Supported by other recent studies.

Significant research has come to the fore since we finished our paper. A Study in New England The current outbreak in the Journal of Medicine involved monkeypox affecting more than 500 people in 16 countries. Although no cases of encephalitis or seizures were reported, monkeypox was found in one in ten people and headache and fatigue in more than a quarter of people with low mood.

However, Spain has recently reported two cases of monkeypox-confirmed encephalitis. Further monitoring is needed to determine the true extent of more serious problems such as encephalitis and seizures.
Monkeypox outbreaks remain a global concern and require ongoing public health measures, including improving access to vaccination.

Although monkeypox primarily causes flu-like symptoms and skin problems, our latest study – and subsequent studies – show that neuropsychiatric symptoms are not uncommon. We are not expecting a tide of serious brain problems, but complications such as encephalitis and seizures can occur in a small proportion of people. We need more research to find out whether these symptoms persist over time and whether they are caused by monkeypox.

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Hello Friends, My Name is Raushan Kumar. I am a Part-Time Blogger and Student. I am author of https://searchnews.in . We're dedicated to providing you the best of News, with a focus on Business, Health, Lifestyle, World, Tech, India, Gadget.
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