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Should kidney transplant recipients consume a low protein diet? here is your answer

New Delhi: According to conventional wisdom, kidney disease patients should consume a low-protein diet. With their recent study on the relationship between protein intake and skeletal muscle mass in kidney transplant recipients, scientists at Osaka Metropolitan University demonstrated that this may not always be the case. Clinical Nutrition published its findings.

Patients with chronic kidney disease have been shown to have induced sarcopenia as a result of chronic inflammation, hypercatabolism, decreased nutrient intake and decreased physical activity, all of which are associated with impaired kidney function. Many of these physiological and metabolic abnormalities can be corrected or corrected as a result of successful kidney transplantation. As a result, kidney transplant recipients gain skeletal muscle mass after receiving a kidney transplant. Because too much protein impairs kidney function, it is widely believed that patients with chronic kidney disease, including kidney transplant recipients, should limit protein intake to protect their kidneys.

On the other hand, severe protein restriction has been linked to worsening sarcopenia and a poor prognosis. Protein intake is thought to be related to skeletal muscle recovery after kidney transplantation as nutritional and exercise therapy is recommended to improve sarcopenia. However, few studies have looked at the link between skeletal muscle mass and protein intake in kidney transplant recipients.

To fill this void, a research team led by Dr. Akihiro Kosoku, Dr. Tomoki Iwai and Professor Junji Uchida at Osaka Metropolitan University’s Department of Urology, Graduate School of Medicine, investigated the relationship between changes in skeletal muscle (as that measured) by bioelectrical impedance analysis) and protein intake (as estimated from urine collected from 64 kidney transplant recipients 12 months after transplantation). The findings showed that changes in skeletal muscle mass were positively correlated with protein intake during this period, and that protein deficiency resulted in decreased muscle mass. “Further research is needed to elucidate optimal protein intake to prevent decline in kidney function or sarcopenia in kidney transplant recipients,” said Iwai and Dr. Kosoku. We hope that nutritional counseling, including protein intake, will improve life expectancy and prognosis.”

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